Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR006557)
Formula
SVG example
Hydrolytic Dehalogenation
Reactant Clofazimine Product Hydrolytic-dehalogenated clofazimine
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 1A2 (CYP1A2) DME Info
Metabolic Type Other reaction - Hydrolytic Dehalogenation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006563 Clofazimine Hydrated clofazimine Other reaction - Hydration Clofazimine [1]
MR006559 Clofazimine Hydrolytic-deaminated clofazimine Hydrolysis - Hydrolytic Deamination Clofazimine [1]
MR006561 Clofazimine Hydroxylated clofazimine Oxidation - Hydrolyzationn Clofazimine [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006558 Hydrolytic-dehalogenated clofazimine Hydrolytic-dehalogenated Clofazimine sulfate Conjugation - sulfation Clofazimine [1]
References
1 Characterization of Clofazimine Metabolism in Human Liver Microsomal Incubation In Vitro

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