Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR006559)
Formula
CYP3A4 ...
SVG example
Hydrolytic Deamination
Reactant Clofazimine Product Hydrolytic-deaminated clofazimine
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Cytochrome P450 3A5 (CYP3A5) DME Info
Metabolic Type Hydrolysis - Hydrolytic Deamination
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006563 Clofazimine Hydrated clofazimine Other reaction - Hydration Clofazimine [1]
MR006557 Clofazimine Hydrolytic-dehalogenated clofazimine Other reaction - Hydrolytic Dehalogenation Clofazimine [1]
MR006561 Clofazimine Hydroxylated clofazimine Oxidation - Hydrolyzationn Clofazimine [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006560 Hydrolytic-deaminated clofazimine Hydrolytic-deaminated clofazimine glucuronide Conjugation - Glucuronidation Clofazimine [1]
References
1 Characterization of Clofazimine Metabolism in Human Liver Microsomal Incubation In Vitro

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