Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR006602)
Formula Reactant M31-Dabrafenib Product Dabrafenib mesylate Metabolite M26
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006601 Desmethyl-dabrafenib M31-Dabrafenib Oxidation - Oxidationn Dabrafenib mesylate [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006603 Dabrafenib mesylate Metabolite M26 Dabrafenib mesylate Metabolite M28 Unclear Dabrafenib mesylate [1]
References
1 Metabolism and disposition of oral dabrafenib in cancer patients: proposed participation of aryl nitrogen in carbon-carbon bond cleavage via decarboxylation following enzymatic oxidation

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.