Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR006662)
Formula
SVG example
Hydrolyzationn
Reactant N-desmethyldoxepin Product Hydroxydesmethyl doxepin
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 2D6 (CYP2D6) DME Info
Metabolic Type Oxidation - Hydrolyzationn
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006661 Doxepin hydrochloride N-desmethyldoxepin Oxidation - N-demethylation Doxepin hydrochloride [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006664 Hydroxydesmethyl doxepin Didesmethyl doxepin Oxidation - N-demethylation Doxepin hydrochloride [1]
MR006663 Hydroxydesmethyl doxepin Hydroxydesmethyl doxepin glucuronide Conjugation - Glucuronidation Doxepin hydrochloride [1]
References
1 Pharmacogenomics knowledge for personalized medicine Clin Pharmacol Ther. 2012 Oct;92(4):414-7. doi: 10.1038/clpt.2012.96.

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.