Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR006670)
Formula Reactant (E)-2-hydroxydoxepin Product Hydroxydoxepin glucuronide
Reactant Info Product Info
Metabolic Type Conjugation - Glucuronidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006668 Doxepin hydrochloride (E)-2-hydroxydoxepin Oxidation - Hydrolyzationn Doxepin hydrochloride [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006669 (E)-2-hydroxydoxepin (E)-2-hydroxy-N-desmethyldoxepin Oxidation - Demethylation Doxepin hydrochloride [2]
References
1 DrugBank(Pharmacology-Metabolism):Doxepin hydrochloride
2 Pharmacogenomics knowledge for personalized medicine Clin Pharmacol Ther. 2012 Oct;92(4):414-7. doi: 10.1038/clpt.2012.96.

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