| General Information of This Metabolic Reaction (MR) (ID:
MR006805) |
| Formula |
Oxidationn; keto-reduction
|
| Reactant |
Boceprevir |
Product |
Boceprevir metabolite M28 |
|
Reactant Info
|
Product Info
|
|
Metabolic Enzyme
|
Aldo-keto reductase 1C2 (AKR1C2)
|
DME Info
|
|
Aldo-keto reductase 1C3 (AKR1C3)
|
DME Info
|
|
Cytochrome P450 3A4 (CYP3A4)
|
DME Info
|
|
Cytochrome P450 3A5 (CYP3A5)
|
DME Info
|
|
Metabolic Type
|
Multi-steps Reaction
-
Oxidationn; keto-reduction
|
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| Other MR(s) Related to The Reactant of This MR |
|
Other MR(s) That Metabolize The Reactant of This MR
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| References |
| 1 |
Characterization of human liver enzymes involved in the biotransformation of boceprevir, a hepatitis C virus protease inhibitor
|
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