Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR006865)
Formula Reactant Enalapril Product Enalaprilat
Reactant Info Product Info
Metabolic Enzyme Carboxylesterase 1 (CES1) DME Info
Metabolic Type Oxidation - Hydrolyzationn
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006866 Enalapril Enalapril demethylation Oxidation - N-Demethylation Enalapril [1]
References
1 Absorption and cleavage of enalapril, a carboxyl ester prodrug, in the rat intestine: in vitro, in situ intestinal perfusion and portal vein cannulation models. Biopharm Drug Dispos. 2015 Sep;36(6):385-397.

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