Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR006943)
Formula
CYP1A2 ...
SVG example
Desulfonization
Reactant Malathion Product Malaoxon
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 1A2 (CYP1A2) DME Info
Cytochrome P450 2B6 (CYP2B6) DME Info
Metabolic Type Other reaction - Desulfonization
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006948 Malathion Dimethyldithiophosphate Other reaction - Desulfonization Malathion [1]
MR006947 Malathion Malathion monocarboxylic acid Hydrolysis - Hydrolysis Malathion [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006946 Malaoxon Dimethylthiophosphate Oxidation - Oxidationn Malathion [1]
MR006944 Malaoxon Malathion monocarboxylic acid Hydrolysis - Hydrolysis Malathion [1]
References
1 Malathion bioactivation in the human liver: the contribution of different cytochrome p450 isoforms. Drug Metab Dispos. 2005 Mar;33(3):295-302.

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