Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR006964)
Formula
CYP3A4 ...
SVG example
Oxidationn
Reactant EPX-100 Product EPX-100 M1
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Mephenytoin 4-hydroxylase (CYP2C19) DME Info
Cytochrome P450 2D6 (CYP2D6) DME Info
Metabolic Type Oxidation - Oxidationn
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006969 EPX-100 EPX-100 M12 Unclear EPX-100 [1]
MR006968 EPX-100 EPX-100 M14 Multi-steps Reaction - Oxidationn; conjugation EPX-100 [1]
MR006967 EPX-100 EPX-100 M19 Oxidation - Oxidationn EPX-100 [1]
MR006965 EPX-100 EPX-100 M2 Oxidation - Oxidationn EPX-100 [1]
MR006966 EPX-100 EPX-100 M6 Oxidation - Oxidationn EPX-100 [1]
References
1 Using chimeric mice with humanized livers to predict human drug metabolism and a drug-drug interaction. J Pharmacol Exp Ther. 2013 Feb;344(2):388-96.

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