Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR006993)
Formula Reactant 3'-Oxohexobarbitall Product Hexobarbital glutathione conjugate derivative
Reactant Info Product Info
Metabolic Enzyme Glutathione S-transferase (GST) DME Info
Metabolic Type Conjugation - Glutathione conjugation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006992 3'-Hydroxyhexobarbital 3'-Oxohexobarbitall Oxidation - Oxidationn VA-10872 [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006994 Hexobarbital glutathione conjugate derivative 1,5-dimethylbarbituric acid Unclear VA-10872 [1]
References
1 Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675.

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