Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR006992)
Formula
SVG example
Oxidationn
Reactant 3'-Hydroxyhexobarbital Product 3'-Oxohexobarbitall
Reactant Info Product Info
Metabolic Enzyme Cytosolic dehydrogenase (CYDH) DME Info
Metabolic Type Oxidation - Oxidationn
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006991 VA-10872 3'-Hydroxyhexobarbital Oxidation - 3'-hydroxylation VA-10872 [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006995 3'-Hydroxyhexobarbital 3'-Hydroxyhexobarbital O-glucuronide Conjugation - Glucuronidation VA-10872 [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006993 3'-Oxohexobarbitall Hexobarbital glutathione conjugate derivative Conjugation - Glutathione conjugation VA-10872 [1]
References
1 Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675.

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