Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR007069)
Formula
SVG example
Reactant Tetrahydrodaidzein Product Equol
Reactant Info Product Info
Metabolic Enzyme tetrahydrodaidzein reductase (THDR) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004165 Dihydrodaidzein Tetrahydrodaidzein Unclear Dihydrodaidzein [1], [2]
MR007068 Dihydrodazein Tetrahydrodaidzein Unclear Daidzein [3]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004166 Tetrahydrodaidzein Dehydroequol Unclear Dihydrodaidzein [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004170 Dihydrogenistein Equol Unclear Dihydrogenistein [4]
MR004167 Dehydroequol Equol Unclear Dihydrodaidzein [1]
MR008590 Dihydrodaidzein Equol Reduction - Reduction Puerarin [5]
References
1 Enantioselective synthesis of S-equol from dihydrodaidzein by a newly isolated anaerobic human intestinal bacterium
2 P212A Mutant of Dihydrodaidzein Reductase Enhances (S)-Equol Production and Enantioselectivity in a Recombinant Escherichia coli Whole-Cell Reaction System
3 Metabolism of Daidzein and Genistein by Gut Bacteria of the Class Coriobacteriia
4 Conversion of daidzein and genistein by an anaerobic bacterium newly isolated from the mouse intestine. Appl Environ Microbiol. 2008 Aug;74(15):4847-52.
5 Pharmacokinetics and drug delivery systems for puerarin, a bioactive flavone from traditional Chinese medicine

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