General Information of This Metabolic Reaction (MR) (ID: MR007068)
Formula
Reactant Dihydrodazein Product Tetrahydrodaidzein
Reactant Info Product Info
Metabolic Enzyme dihydrodaidzein reductase (DHDR) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007067 Daidzein Dihydrodazein Reduction - Reduction Daidzein [1]
MR004169 Dihydrodaidzein Dihydrodaidzein Unclear Dihydrodaidzein [2]
MR008589 Puerarin metabolite M50 Dihydrodaidzein Reduction - Reduction Puerarin [3]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007070 Dihydrodazein O-desmethylangolensin Unclear Daidzein [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004165 Dihydrodaidzein Tetrahydrodaidzein Unclear Dihydrodaidzein [4], [5]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004166 Tetrahydrodaidzein Dehydroequol Unclear Dihydrodaidzein [4]
MR004168 Tetrahydrodaidzein Equol Unclear Dihydrodaidzein [4]
MR007069 Tetrahydrodaidzein Equol Unclear Daidzein [1]
References
1 Metabolism of Daidzein and Genistein by Gut Bacteria of the Class Coriobacteriia
2 R(-)-O-desmethylangolensin is the main enantiomeric form of daidzein metabolite produced by human in vitro and in vivo
3 Pharmacokinetics and drug delivery systems for puerarin, a bioactive flavone from traditional Chinese medicine
4 Enantioselective synthesis of S-equol from dihydrodaidzein by a newly isolated anaerobic human intestinal bacterium
5 P212A Mutant of Dihydrodaidzein Reductase Enhances (S)-Equol Production and Enantioselectivity in a Recombinant Escherichia coli Whole-Cell Reaction System

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