Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR007076)
Formula	CYP3A4 ... Demethylation
	Reactant	Dapoxetine Metabolite M1	Product	Desmethyldapoxetine
	Reactant	Reactant Info	Product	Product Info
Metabolic Enzyme	Cytochrome P450 3A4 (CYP3A4)				DME Info
Metabolic Enzyme	Cytochrome P450 2D6 (CYP2D6)				DME Info
Metabolic Type	Oxidation - Demethylation

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Produce The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR007073	Dapoxetine	Dapoxetine Metabolite M1	Oxidation - N-dealkylation	Dapoxetine	[1]

Other MR(s) That Metabolize The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR007074	Dapoxetine Metabolite M1	Dapoxetine Metabolite M2	Oxidation - Hydrolyzationn	Dapoxetine	[1]

References
1	Characterization of Phase I Hepatic Metabolites of Anti-Premature Ejaculation Drug Dapoxetine by UHPLC-ESI-Q-TOF

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