Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR007081)
Formula
SVG example
Oxidationn
Reactant Dapoxetine Product Dapoxetine-n-oxide
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 2D6 (CYP2D6) DME Info
Metabolic Type Oxidation - Oxidationn
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007073 Dapoxetine Dapoxetine Metabolite M1 Oxidation - N-dealkylation Dapoxetine [1]
MR007079 Dapoxetine Dapoxetine Metabolite M11 Other reaction - Deacylation Dapoxetine [1]
MR007077 Dapoxetine Dapoxetine Metabolite M3 Oxidation - Hydrolyzationn Dapoxetine [1]
MR007083 Dapoxetine Dapoxetine Metabolite M7 Oxidation - Hydrolyzationn Dapoxetine [1]
MR007085 Dapoxetine Didesmethyldapoxetine Unclear Dapoxetine [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007082 Dapoxetine-n-oxide Dapoxetine Metabolite M10 Oxidation - Hydrolyzationn Dapoxetine [1]
References
1 Characterization of Phase I Hepatic Metabolites of Anti-Premature Ejaculation Drug Dapoxetine by UHPLC-ESI-Q-TOF
2 Dapoxetine: a new option in the medical management of premature ejaculation. Ther Adv Urol. 2012 Oct;4(5):233-51.

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.