Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR007405)
Formula
CYP2D6 ...
SVG example
O-demethylation
Reactant CCRIS-9277 Product HHMA
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 2D6 (CYP2D6) DME Info
Catechol O-methyltransferase (COMT) DME Info
Metabolic Type Oxidation - O-demethylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007394 CCRIS-9277 MDA Oxidation - O-demethylation CCRIS-9277 [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007406 HHMA HHA Oxidation - N-dealkylation CCRIS-9277 [1]
MR007408 HHMA HMMA Oxidation - O-demethylation CCRIS-9277 [1]
References
1 Human pharmacology of MDMA: pharmacokinetics, metabolism, and disposition. Ther Drug Monit. 2004 Apr;26(2):137-44.

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