Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR007408)
Formula Reactant HHMA Product HMMA
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 2D6 (CYP2D6) DME Info
Catechol O-methyltransferase (COMT) DME Info
Metabolic Type Oxidation - O-demethylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007405 CCRIS-9277 HHMA Oxidation - O-demethylation CCRIS-9277 [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007406 HHMA HHA Oxidation - N-dealkylation CCRIS-9277 [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007409 HMMA CCRIS-9277 M10 Conjugation - Conjugation CCRIS-9277 [1]
References
1 Human pharmacology of MDMA: pharmacokinetics, metabolism, and disposition. Ther Drug Monit. 2004 Apr;26(2):137-44.

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