General Information of This Metabolic Reaction (MR) (ID: MR012928)
Formula
SVG example
Hydrolyzationn
Reactant UDP-galactose Product Galactose-1-phosphate
Reactant Info Product Info
Metabolic Enzyme Choline glycerophosphodiester phosphodiesterase (ENPP6) DME Info
Metabolic Type Oxidation - Hydrolyzationn
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012934 UDP-galactose Galactose Oxidation - Hydrolyzationn UDP-galactose [1]
MR012930 UDP-galactose UDP-glc Unclear UDP-galactose [2]
MR004474 UDP-galactose UDP-glc Unclear UDP-glucose [3]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000159 Alpha-D-galactose Alpha-D-galactose 1-phosphate Other reaction - Phosphorylation; Galactokinase Alpha-D-galactose [4], [5], [6]
MR007412 CERC-801 Galactose-1-phosphate Unclear CERC-801 [7]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012929 Galactose-1-phosphate UDP-galactose Unclear UDP-galactose [2]
MR004473 Galactose-1-phosphate UDP-galactose Unclear UDP-glucose [3]
References
1 Using a Personal Glucose Meter and Alkaline Phosphatase for Point-of-Care Quantification of Galactose-1-Phosphate Uridyltransferase in Clinical Galactosemia Diagnosis
2 UDP-galactose 4'-epimerase activities toward UDP-Gal and UDP-GalNAc play different roles in the development of Drosophila melanogaster
3 Defects in Galactose Metabolism and Glycoconjugate Biosynthesis in a UDP-Glucose Pyrophosphorylase-Deficient Cell Line Are Reversed by Adding Galactose to the Growth Medium
4 Molecular structure of galactokinase J Biol Chem. 2003 Aug 29;278(35):33305-11. doi: 10.1074/jbc.M304789200.
5 Enzymatic production of alpha-D-galactose 1-phosphate by lactose phosphorolysis Biotechnol Lett. 2009 Dec;31(12):1873-7. doi: 10.1007/s10529-009-0087-1.
6 The Antifungal Effects of Citral on Magnaporthe oryzae Occur via Modulation of Chitin Content as Revealed by RNA-Seq Analysis. J Fungi (Basel). 2021 Nov 29;7(12):1023. doi: 10.3390/jof7121023.
7 Molecular and biochemical characterization of human galactokinase and its small molecule inhibitors. Chem Biol Interact. 2010 Dec 5;188(3):376-85.

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