Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR007419)
Formula
SVG example
Reactant Quinone Product CE-122738
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR008146 Quinone Hydroquinone Unclear - Unclear Phytonadione [1]
MR007627 Quinone Tetrahydroxydipheno-o-quinone Unclear Pyrogallol [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007420 CE-122738 CE-122738 Glucuronide Conjugation - Glucuronidation CP-122721 [3], [4]
References
1 Recent trends in the metabolism and cell biology of vitamin K with special reference to vitamin K cycling and MK-4 biosynthesis
2 Metabolism of pyrogallol to purpurogallin by human erythrocytic hemoglobin
3 In vitro metabolism of CP-122,721 ((2S,3S)-2-phenyl-3-[(5-trifluoromethoxy-2-methoxy)benzylamino]piperidine), a non-peptide antagonist of the substance P receptor. Drug Metab Pharmacokinet. 2007 Oct;22(5):336-49.
4 Metabolism, pharmacokinetics, and excretion of the substance P receptor antagonist CP-122,721 in humans: structural characterization of the novel major circulating metabolite 5-trifluoromethoxy salicylic acid by high-performance liquid chromatography-tandem mass spectrometry and NMR spectroscopy

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