Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR007434)
Formula Reactant CYC-202 Product PMF30-128
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007428 CYC-202 CYC-202 M1 Oxidation - Oxidationn CYC-202 [1]
MR007429 CYC-202 CYC-202 M2 Oxidation - N-dealkylation CYC-202 [1]
MR007430 CYC-202 CYC-202 M3 Oxidation - Oxidationn CYC-202 [1]
MR007431 CYC-202 CYC-202 M4 Oxidation - N-dealkylation CYC-202 [1]
MR007432 CYC-202 CYC-202 M5 Oxidation - Oxidationn CYC-202 [1]
MR007435 CYC-202 CYC-202 M6 Conjugation - Glucuronidation CYC-202 [1]
MR007436 CYC-202 CYC-202 M7 Unclear CYC-202 [1]
MR007433 CYC-202 Met-4 Unclear CYC-202 [1]
References
1 Metabolism of the trisubstituted purine cyclin-dependent kinase inhibitor seliciclib (R-roscovitine) in vitro and in vivo. Drug Metab Dispos. 2008 Mar;36(3):561-70.

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