Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR007486)
Formula Reactant Antipyrine Product Norantipyrine
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 2C8 (CYP2C8) DME Info
Cytochrome P450 2C9 (CYP2C9) DME Info
Mephenytoin 4-hydroxylase (CYP2C19) DME Info
Cytochrome P450 1A2 (CYP1A2) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007488 Antipyrine 3-OH-methylantipyrine Oxidation - Hydrolyzationn Antipyrine [1]
MR007487 Antipyrine 4-OH-antipyrine Oxidation - Hydrolyzationn Antipyrine [1]
References
1 Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675.

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