Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR007633)
Formula
SVG example
Hydrolyzationn
Reactant Licofelone acyl glucuronide (M1) Product Licofelone M3
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 2C8 (CYP2C8) DME Info
Metabolic Type Oxidation - Hydrolyzationn
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007632 ML-3000 Licofelone acyl glucuronide (M1) Conjugation - Acyl glucuronidation ML-3000 [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007635 Licofelone M2 Licofelone M3 Conjugation - Acyl glucuronidation ML-3000 [1]
References
1 Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675.

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