Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR008290)
Formula	Amide hydrolysis
	Reactant	BIIB074	Product	BIIB074 metabolite M14
	Reactant	Reactant Info	Product	Product Info
Metabolic Type	Hydrolysis - Amide hydrolysis

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Metabolize The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR008293	BIIB074	BIIB074 metabolite M10	Unclear - Unclear	BIIB074	[1]
MR008292	BIIB074	BIIB074 metabolite M13	Conjugation - N-carbamoyl glucuronidation	BIIB074	[1]

Other MR(s) Related to The Product of This MR

Other MR(s) That Metabolize The Produtc of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR008291	BIIB074 metabolite M14	BIIB074 metabolite M16	Hydrolysis - Amide hydrolysis	BIIB074	[1]

References
1	Evaluation of the Pharmacokinetic Interaction Between the Voltage- and Use-Dependent Nav1.7 Channel Blocker Vixotrigine and Carbamazepine in Healthy Volunteers

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