Details of the Metabolic Reaction (MR) | INTEDE

General Information of This Metabolic Reaction (MR) (ID: MR008293)
Formula	UGT Unclear
	Reactant	BIIB074		Product	BIIB074 metabolite M10
	Reactant	Reactant Info		Product	Product Info
Metabolic Enzyme	UDP-glucuronyltransferase (UGT)					DME Info
Metabolic Type	Unclear - Unclear

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Metabolize The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR008292	BIIB074	BIIB074 metabolite M13	Conjugation - N-carbamoyl glucuronidation	BIIB074	[1]
MR008290	BIIB074	BIIB074 metabolite M14	Hydrolysis - Amide hydrolysis	BIIB074	[1]

References
1	Evaluation of the Pharmacokinetic Interaction Between the Voltage- and Use-Dependent Nav1.7 Channel Blocker Vixotrigine and Carbamazepine in Healthy Volunteers

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