Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR008298)
Formula Reactant LJN452 metabolite M24 Product LJN452 metabolite M19.5
Reactant Info Product Info
Metabolic Type Oxidation - Oxidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR008296 LJN452 LJN452 metabolite M24 Unclear - Unclear LJN452 [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR008299 LJN452 metabolite M24 LJN452 metabolite M18.1 Other reaction - Hydration LJN452 [1]
MR008297 LJN452 metabolite M24 LJN452 metabolite M18.2 Oxidation - Oxidation LJN452 [1]
References
1 Evaluation of the Absorption, Metabolism, and Excretion of a Single Oral 1-mg Dose of Tropifexor in Healthy Male Subjects and the Concentration Dependence of Tropifexor Metabolism

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