Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR008301)
Formula	Reactant	LJN452 metabolite M11.6	Product	LJN452 metabolite M6
Formula	Reactant	Reactant Info	Product	Product Info
Metabolic Type	Oxidation - Oxidation

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Produce The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR008300	LJN452	LJN452 metabolite M11.6	Multi-steps Reaction - Oxidative; O-dealkylation	LJN452	[1]

Other MR(s) That Metabolize The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR008302	LJN452 metabolite M11.6	LJN452 metabolite M6.7	Conjugation - Glucuronidation	LJN452	[1]

References
1	Evaluation of the Absorption, Metabolism, and Excretion of a Single Oral 1-mg Dose of Tropifexor in Healthy Male Subjects and the Concentration Dependence of Tropifexor Metabolism

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