Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR008302)
Formula Reactant LJN452 metabolite M11.6 Product LJN452 metabolite M6.7
Reactant Info Product Info
Metabolic Type Conjugation - Glucuronidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR008300 LJN452 LJN452 metabolite M11.6 Multi-steps Reaction - Oxidative; O-dealkylation LJN452 [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR008301 LJN452 metabolite M11.6 LJN452 metabolite M6 Oxidation - Oxidation LJN452 [1]
References
1 Evaluation of the Absorption, Metabolism, and Excretion of a Single Oral 1-mg Dose of Tropifexor in Healthy Male Subjects and the Concentration Dependence of Tropifexor Metabolism

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