Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR008316)
Formula
SVG example
Glucose conjugation
Reactant ABT-126 Product ABT-126 metabolite M12
Reactant Info Product Info
Metabolic Type Conjugation - Glucose conjugation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR008312 ABT-126 ABT-126 metabolite M1 Oxidation - Oxidation ABT-126 [1]
MR008319 ABT-126 ABT-126 metabolite M10 Multi-steps Reaction - Oxidation; cysteine conjugation ABT-126 [1]
MR008317 ABT-126 ABT-126 metabolite M11 Conjugation - Glucuronidation ABT-126 [1]
MR008318 ABT-126 ABT-126 metabolite M7 Multi-steps Reaction - Di-oxidation; sulfation ABT-126 [1]
MR008315 ABT-126 ABT-126 metabolite M8 Multi-steps Reaction - Oxidation; glucuronidation ABT-126 [1]
References
1 Metabolism and Disposition of a Novel Selective 7 Neuronal Acetylcholine Receptor Agonist ABT-126 in Humans: Characterization of the Major Roles for Flavin-Containing Monooxygenases and UDP-Glucuronosyl Transferase 1A4 and 2B10 in Catalysis

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