Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR008319)
Formula Reactant ABT-126 Product ABT-126 metabolite M10
Reactant Info Product Info
Metabolic Type Multi-steps Reaction - Oxidation; cysteine conjugation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR008312 ABT-126 ABT-126 metabolite M1 Oxidation - Oxidation ABT-126 [1]
MR008317 ABT-126 ABT-126 metabolite M11 Conjugation - Glucuronidation ABT-126 [1]
MR008316 ABT-126 ABT-126 metabolite M12 Conjugation - Glucose conjugation ABT-126 [1]
MR008318 ABT-126 ABT-126 metabolite M7 Multi-steps Reaction - Di-oxidation; sulfation ABT-126 [1]
MR008315 ABT-126 ABT-126 metabolite M8 Multi-steps Reaction - Oxidation; glucuronidation ABT-126 [1]
References
1 Metabolism and Disposition of a Novel Selective 7 Neuronal Acetylcholine Receptor Agonist ABT-126 in Humans: Characterization of the Major Roles for Flavin-Containing Monooxygenases and UDP-Glucuronosyl Transferase 1A4 and 2B10 in Catalysis

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