Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR008425)
Formula
CYP3A4 ...
SVG example
Hydroxylation
Reactant STX 64 Product STX 64 metabolite M13
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Cytochrome P450 3A5 (CYP3A5) DME Info
Cytochrome P450 2C9 (CYP2C9) DME Info
Cytochrome P450 2C8 (CYP2C8) DME Info
Metabolic Type Oxidation - Hydroxylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR008428 STX 64 667-Coumarin Unclear - Unclear STX 64 [1]
MR008436 STX 64 STX 64 metabolite M14 Oxidation - Hydroxylation STX 64 [1]
MR008434 STX 64 STX 64 metabolite M18 Unclear - Unclear STX 64 [1]
MR008432 STX 64 STX 64 metabolite M7 Oxidation - Hydroxylation STX 64 [1]
MR008443 STX 64 STX 64 metabolite M9 Oxidation - Hydroxylation STX 64 [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR008426 STX 64 metabolite M13 STX 64 metabolite M16 Oxidation - Hydroxylation STX 64 [1]
References
1 In vitro metabolism of irosustat, a novel steroid sulfatase inhibitor: interspecies comparison, metabolite identification, and metabolic enzyme identification

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