Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR008515)
Formula	CYP3A4 ... Demethylation
	Reactant	SAM-531	Product	Desmethylcerlapirdine
	Reactant	Reactant Info	Product	Product Info
Metabolic Enzyme	Cytochrome P450 3A4 (CYP3A4)				DME Info
Metabolic Enzyme	Cytochrome P450 2C8 (CYP2C8)				DME Info
Metabolic Type	Oxidation - Demethylation

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Metabolize The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR008516	SAM-531	Cerapirdine-N-oxide	Oxidation - N-oxidation	SAM-531	[1]

References
1	Disposition and metabolic profiling of [(14)C]cerlapirdine using accelerator mass spectrometry

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