Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR009195)
Formula
SVG example
Dehydroxylation
Reactant 3-(Dihydroxyphenyl)propanoic acid Product 3-(3'-Hydroxyphenyl)propanoic acid
Reactant Info Product Info
Metabolic Type Oxidation - Dehydroxylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009194 3,4-Dihydroxycinnamic Acid 3-(Dihydroxyphenyl)propanoic acid Reduction - Reduction 3,4-Dihydroxycinnamic Acid [1], [2]
MR013001 Perillic acid (PCOOH) Cis-Dihydroperillic Acid Unclear - Unclear Perillyl alcohol [3]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009200 3-(Dihydroxyphenyl)propanoic acid DHFA Unclear - Unclear 3,4-Dihydroxycinnamic Acid [2]
MR009202 3-(Dihydroxyphenyl)propanoic acid O-quinone Unclear - Unclear 3,4-Dihydroxycinnamic Acid [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006953 AS-63093 3-(3-Hydroxyphenyl)propanoic acid Unclear AS-63093 [4]
MR004496 3-(3',4'-Dihydroxyphenyl)propionic acid 3-(3'-Hydroxyphenyl)propionic acid Reduction - Dehydroxylation VS-12343 [5]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009196 3-(3'-Hydroxyphenyl)propanoic acid 3-(phenyl)propanoic acid Oxidation - Dehydroxylation 3,4-Dihydroxycinnamic Acid [1]
MR004499 3-(3'-Hydroxyphenyl)propionic acid 3'-Hydroxyphenylacetic acid Unclear VS-12343 [5]
MR004497 3-(3'-Hydroxyphenyl)propionic acid 3-(phenyl)propionic acid Reduction - Dehydroxylation VS-12343 [5]
References
1 In vitro catabolism of 3',4'-dihydroxycinnamic acid by human colonic microbiota
2 Metabolism of caffeic acid by isolated rat hepatocytes and subcellular fractions
3 Gas chromatographic-mass spectrometric analysis of perillyl alcohol and metabolites in plasma
4 Studies on pharmacokinetic drug interaction potential of vinpocetine. Medicines (Basel). 2015 Jun 5;2(2):93-105.
5 Biotransformation of two citrus flavanones by lactic acid bacteria in chemical defined medium

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