Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR004497)
Formula
SVG example
Dehydroxylation
Reactant 3-(3'-Hydroxyphenyl)propionic acid Product 3-(phenyl)propionic acid
Reactant Info Product Info
Metabolic Type Reduction - Dehydroxylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006953 AS-63093 3-(3-Hydroxyphenyl)propanoic acid Unclear AS-63093 [1]
MR009195 3-(Dihydroxyphenyl)propanoic acid 3-(3'-Hydroxyphenyl)propanoic acid Oxidation - Dehydroxylation 3,4-Dihydroxycinnamic Acid [2]
MR004496 3-(3',4'-Dihydroxyphenyl)propionic acid 3-(3'-Hydroxyphenyl)propionic acid Reduction - Dehydroxylation VS-12343 [3]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004499 3-(3'-Hydroxyphenyl)propionic acid 3'-Hydroxyphenylacetic acid Unclear VS-12343 [3]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003834 3-(4-Hydroxyphenyl) propionic acid 3-Phenylpropionic acid Unclear BE-14348A [4]
MR006961 3-(4-Hydroxyphenyl)propionic acid 3-(Phenyl)propionic acid Unclear CCG-208408 [5]
MR004313 3-(4'-hydroxyphenyl)propionic acid 3-Phenylpropionic acid Reduction - Dehydroxylation Naringin [6]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003835 3-Phenylpropionic acid Benzoic acid Unclear BE-14348A [4]
MR009197 3-(phenyl)propanoic acid 3-(phenyl)acetic acid Oxidation - Oxidation 3,4-Dihydroxycinnamic Acid [2]
MR006962 3-(Phenyl)propionic acid Hippuric acid Unclear CCG-208408 [5]
MR004498 3-(phenyl)propionic acid Phenylacetic acid Unclear VS-12343 [3]
References
1 Studies on pharmacokinetic drug interaction potential of vinpocetine. Medicines (Basel). 2015 Jun 5;2(2):93-105.
2 In vitro catabolism of 3',4'-dihydroxycinnamic acid by human colonic microbiota
3 Biotransformation of two citrus flavanones by lactic acid bacteria in chemical defined medium
4 High gastrointestinal permeability and local metabolism of naringenin: influence of antibiotic treatment on absorption and metabolism
5 Catabolism of citrus flavanones by the probiotics Bifidobacterium longum and Lactobacillus rhamnosus. Eur J Nutr. 2018 Feb;57(1):231-242.
6 Microbial Metabolism of Naringin and the Impact on Antioxidant Capacity

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