Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR009581)
Formula	Glucuronidation
	Reactant	N-Desmethylrosiglitazone	Product	N-Desmethyl glucuronide rosiglitazone
	Reactant	Reactant Info	Product	Product Info
Metabolic Type	Conjugation - Glucuronidation

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Produce The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR009576	Rosiglitazone	N-Desmethylrosiglitazone	Oxidation - N-demethylation	Rosiglitazone	[1]

Other MR(s) That Metabolize The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR009579	N-Desmethylrosiglitazone	N-Desmethyl-ortho-hydroxy rosiglitazone	Oxidation - Hydroxylation	Rosiglitazone	[1]
MR009577	N-Desmethylrosiglitazone	N-Desmethyl-para-hydroxy rosiglitazone	Oxidation - Hydroxylation	Rosiglitazone	[1]

References
1	Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675.

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