Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR009591)
Formula
SVG example
N-oxidation
Reactant Rosiglitazone Product Phenoxyacetic acid derivative of rosiglitazone
Reactant Info Product Info
Metabolic Type Oxidation - N-oxidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009576 Rosiglitazone N-Desmethylrosiglitazone Oxidation - N-demethylation Rosiglitazone [1]
MR009590 Rosiglitazone N-Despyridinyl rosiglitazone Unclear - Unclear Rosiglitazone [1]
MR009586 Rosiglitazone Ortho-Hydroxyrosiglitazone Oxidation - Hydroxylation Rosiglitazone [1]
MR009582 Rosiglitazone Para-Hydroxyrosiglitazone Oxidation - Hydroxylation Rosiglitazone [1]
References
1 Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675.

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