Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR009621)
Formula
SVG example
Unclear
Reactant BAF-312 Product Siponimod M1
Reactant Info Product Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009622 BAF-312 Siponimod M17 Unclear - Unclear BAF-312 [1]
MR009611 BAF-312 Siponimod M2 Unclear - Unclear BAF-312 [1]
MR009618 BAF-312 Siponimod M5 Oxidation - Hydroxylation BAF-312 [1]
MR009616 BAF-312 Siponimod M6 Oxidation - Hydroxylation BAF-312 [1]
MR009614 BAF-312 Siponimod M7 Oxidation - Hydroxylation BAF-312 [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002272 Siponimod Siponimod metabolite M1 Oxidation - Hydroxylation Siponimod [1]
MR009612 Siponimod M2 Siponimod M1 Unclear - Unclear BAF-312 [1]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009613 Siponimod M1 Siponimod M8 Unclear - Unclear BAF-312 [1]
References
1 Metabolism and disposition of siponimod, a novel selective S1P1/S1P5 agonist, in healthy volunteers and in vitro identification of human cytochrome P450 enzymes involved in its oxidative metabolism. Drug Metab Dispos. 2018 Jul;46(7):1001-1013.

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