Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR009882)
Formula
CYP3A4 ...
SVG example
Unclear
Reactant Avanafil Product Avanafil Metabolite M4-1
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Cytochrome P450 2C9 (CYP2C9) DME Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009880 Avanafil Avanafil Metabolite M1 Unclear - Unclear Avanafil [1], [2]
MR009884 Avanafil Avanafil Metabolite M16 Unclear - Unclear Avanafil [1], [2]
MR009881 Avanafil Avanafil Metabolite M2 Unclear - Unclear Avanafil [1], [2]
MR009883 Avanafil Avanafil Metabolite M4-2 Unclear - Unclear Avanafil [1], [2]
References
1 LC-MS/MS determination of avanafil and its metabolites in rat plasma and brain: pharmacokinetic study after oral administration and transdermal film application
2 FDA:Avanafil

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