Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR009885)
Formula
CYP3A4 ...
SVG example
Unclear
Reactant Axitinib Product Axitinib Metabolite M12
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Cytochrome P450 3A5 (CYP3A5) DME Info
Mephenytoin 4-hydroxylase (CYP2C19) DME Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009890 Axitinib Axitinib Metabolite M12a Unclear - Unclear axitinib [1]
MR009891 Axitinib Axitinib Metabolite M14 Unclear - Unclear axitinib [1]
MR009888 Axitinib Axitinib Metabolite M7 Unclear - Unclear axitinib [1]
MR009889 Axitinib Axitinib Metabolite M8b Unclear - Unclear axitinib [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009887 Axitinib Metabolite M12 Axitinib Metabolite M15 Unclear - Unclear axitinib [1]
MR009886 Axitinib Metabolite M12 Axitinib Metabolite M9 Unclear - Unclear axitinib [1]
References
1 In Vitro Kinetic Characterization of Axitinib Metabolism

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