| General Information of Drug Metabolite (DM) (ID: DM018058) |
| DM Name |
Axitinib Metabolite M14
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| Structure |
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3D MOL is unavailable
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2D MOL is unavailable
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
|
Cytochrome P450 1A2 (CYP1A2)
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DME0003
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| Unclear - Unclear |
Axitinib
|
[1] |
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Cytochrome P450 3A4 (CYP3A4)
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DME0001
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| Unclear - Unclear |
Axitinib
|
[1] |
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Cytochrome P450 3A5 (CYP3A5)
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DME0012
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| Unclear - Unclear |
Axitinib
|
[1] |
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Mephenytoin 4-hydroxylase (CYP2C19)
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DME0021
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| Unclear - Unclear |
Axitinib
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[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| Axitinib |
DR0162
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Approved |
Renal cell carcinoma |
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| References |
| 1 |
In Vitro Kinetic Characterization of Axitinib Metabolism
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