Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR009936)
Formula Reactant Cisapride Product Norcisapride
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Metabolic Type Unclear - N-deataelon
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009938 Cisapride Cisapride Metabolite M2 Oxidation - O-dealkylation Cisapride [1]
MR009937 Cisapride Cisapride Metabolite M4 Oxidation - N-oxidation Cisapride [1]
MR009941 Cisapride Cisapride Metabolite M5 Oxidation - Aromatic hydroxylation NIH-shift Cisapride [1]
MR009939 Cisapride Cisapride Metabolite M6 Oxidation - O-dealkylation Cisapride [1]
MR009940 Cisapride Cisapride Metabolite M7 Oxidation - Aromatic hydroxylation NIH-shift Cisapride [1]
References
1 Identification of the cytochrome P450 enzymes involved in the metabolism of cisapride: in vitro studies of potential co-medication interactions. Br J Pharmacol. 2000 Apr;129(8):1655-67.

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