Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR010136)
Formula Reactant (+)-JQ1 Product (+)-JQ1 Metabolite M7
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Cytochrome P450 2C9 (CYP2C9) DME Info
Mephenytoin 4-hydroxylase (CYP2C19) DME Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR010130 (+)-JQ1 (+)-JQ1 Metabolite M1 Unclear - Unclear (+)-JQ1 [1]
MR010131 (+)-JQ1 (+)-JQ1 Metabolite M2 Unclear - Unclear (+)-JQ1 [1]
MR010132 (+)-JQ1 (+)-JQ1 Metabolite M3 Unclear - Unclear (+)-JQ1 [1]
MR010133 (+)-JQ1 (+)-JQ1 Metabolite M4 Unclear - Unclear (+)-JQ1 [1]
MR010134 (+)-JQ1 (+)-JQ1 Metabolite M5 Unclear - Unclear (+)-JQ1 [1]
MR010135 (+)-JQ1 (+)-JQ1 Metabolite M6 Unclear - Unclear (+)-JQ1 [1]
MR010137 (+)-JQ1 (+)-JQ1 Metabolite M8 Unclear - Unclear (+)-JQ1 [1]
MR010138 (+)-JQ1 (+)-JQ1 Metabolite M9 Unclear - Unclear (+)-JQ1 [1]
References
1 Metabolism of JQ1, an inhibitor of bromodomain and extra terminal bromodomain proteins, in human and mouse liver microsomes?

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