Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR010245)
Formula
SVG example
Oxidation
Reactant Tolcapone Product Tolcapone Metabolite M2
Reactant Info Product Info
Metabolic Type Oxidation - Oxidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR010253 Tolcapone Tolcapone Metabolite M3 Reduction - Reduction Tolcapone [1]
MR010251 Tolcapone Tolcapone Metabolite M4 Conjugation - Glucuronidation Tolcapone [2]
MR010255 Tolcapone Tolcapone Metabolite M5 Conjugation - Sulfation Tolcapone [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR010246 Tolcapone Metabolite M2 Tolcapone Metabolite M6 Conjugation - Sulfation Tolcapone [1]
MR010250 Tolcapone Metabolite M2 Tolcapone Metabolite M7 Oxidation - Oxidation Tolcapone [1]
MR010248 Tolcapone Metabolite M2 Tolcapone Metabolite M8 Oxidation - Methylation Tolcapone [1]
References
1 Analysis of an Integrated Human Multiorgan Microphysiological System for Combined Tolcapone Metabolism and Brain Metabolomics
2 Metabolism and excretion of tolcapone, a novel inhibitor of catechol-O-methyltransferase

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