Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR010253)
Formula
SVG example
Reduction
Reactant Tolcapone Product Tolcapone Metabolite M3
Reactant Info Product Info
Metabolic Type Reduction - Reduction
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR010245 Tolcapone Tolcapone Metabolite M2 Oxidation - Oxidation Tolcapone [1]
MR010251 Tolcapone Tolcapone Metabolite M4 Conjugation - Glucuronidation Tolcapone [2]
MR010255 Tolcapone Tolcapone Metabolite M5 Conjugation - Sulfation Tolcapone [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR010254 Tolcapone Metabolite M3 Tolcapone Metabolite M11 Conjugation - Sulfation Tolcapone [1]
References
1 Analysis of an Integrated Human Multiorgan Microphysiological System for Combined Tolcapone Metabolism and Brain Metabolomics
2 Metabolism and excretion of tolcapone, a novel inhibitor of catechol-O-methyltransferase

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