General Information of This Metabolic Reaction (MR) (ID: MR010255)
Formula
SVG example
Sulfation
Reactant Tolcapone Product Tolcapone Metabolite M5
Reactant Info Product Info
Metabolic Type Conjugation - Sulfation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR010245 Tolcapone Tolcapone Metabolite M2 Oxidation - Oxidation Tolcapone [1]
MR010253 Tolcapone Tolcapone Metabolite M3 Reduction - Reduction Tolcapone [1]
MR010251 Tolcapone Tolcapone Metabolite M4 Conjugation - Glucuronidation Tolcapone [2]
References
1 Analysis of an Integrated Human Multiorgan Microphysiological System for Combined Tolcapone Metabolism and Brain Metabolomics
2 Metabolism and excretion of tolcapone, a novel inhibitor of catechol-O-methyltransferase

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