General Information of This Metabolic Reaction (MR) (ID: MR010335)
Formula
AAM
SVG example
Unclear
Reactant Galocitabine Product 5'-DFCR
Reactant Info Product Info
Metabolic Enzyme Acylamidase (AAM) DME Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002523 Capecitabine 5'-DFCR Hydrolysis - Hydrolysis Capecitabine [1], [2]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002521 5'-DFCR 5'-DFUR Unclear Capecitabine [1], [2]
MR010336 5'-DFCR 5'-DFUR Unclear - Unclear Galocitabine [3]
References
1 EUCRISA? (crisaborole) ointment, 2%, for topical use
2 A new, validated HPLC-MS/MS method for the simultaneous determination of the anti-cancer agent capecitabine and its metabolites: 5'-deoxy-5-fluorocytidine, 5'-deoxy-5-fluorouridine, 5-fluorouracil and 5-fluorodihydrouracil, in human plasma
3 Modified high-performance liquid chromatographic method for analysis of drotaverine in human plasma

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