Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR010336)
Formula
CDA
SVG example
Unclear
Reactant 5'-DFCR Product 5'-DFUR
Reactant Info Product Info
Metabolic Enzyme Cytidine aminohydrolase (CDA) DME Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002523 Capecitabine 5'-DFCR Hydrolysis - Hydrolysis Capecitabine [1], [2]
MR010335 Galocitabine 5'-DFCR Unclear - Unclear Galocitabine [3]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002522 5'-DFUR 5-fluorouracil Hydrolysis - Hydrolysis Capecitabine [1], [2]
MR010337 5'-DFUR 5-FU Unclear - Unclear Galocitabine [4]
References
1 EUCRISA? (crisaborole) ointment, 2%, for topical use
2 A new, validated HPLC-MS/MS method for the simultaneous determination of the anti-cancer agent capecitabine and its metabolites: 5'-deoxy-5-fluorocytidine, 5'-deoxy-5-fluorouridine, 5-fluorouracil and 5-fluorodihydrouracil, in human plasma
3 Simultaneous determination of a new anticancer drug galocitabine and its metabolites in blood by high-performance liquid chromatography
4 Measurement of ascorbic acid in human aqueous humour and plasma and bovine aqueous humour by high-performance liquid chromatography with electrochemical detection

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