Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR010456)
Formula Reactant Oprozomib Product Oprozomib Metabolite M8
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR010452 Oprozomib Oprozomib Metabolite M4 Unclear - Unclear Oprozomib [1]
MR010453 Oprozomib Oprozomib Metabolite M5 Unclear - Unclear Oprozomib [1]
MR010454 Oprozomib Oprozomib Metabolite M6 Unclear - Unclear Oprozomib [1]
MR010455 Oprozomib Oprozomib Metabolite M7 Unclear - Unclear Oprozomib [1]
MR010457 Oprozomib Oprozomib Metabolite M9 Unclear - Unclear Oprozomib [1]
MR010450 Oprozomib PR-025 Unclear - Unclear Oprozomib [1]
MR010448 Oprozomib PR-176 Unclear - Unclear Oprozomib [1]
References
1 In Vitro Metabolism of Oprozomib, an Oral Proteasome Inhibitor: Role of Epoxide Hydrolases and Cytochrome P450s

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