Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR010728)
Formula
SVG example
Unclear
Reactant Nicorandil Product Nicotinic acid
Reactant Info Product Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR010731 Nicorandil Alcohol metabolite Unclear - Unclear Nicorandil [1]
MR010725 Nicorandil Nicorandil Metabolite M1 Unclear - Unclear Nicorandil [1]
MR010726 Nicorandil Nicorandil Metabolite M2 Unclear - Unclear Nicorandil [1]
MR010727 Nicorandil Nicorandil Metabolite M3(N-methyl nicotinamide) Unclear - Unclear Nicorandil [1]
MR010729 Nicorandil Nicotinamide Unclear - Unclear Nicorandil [1]
MR010730 Nicorandil Nicotinuric acid Unclear - Unclear Nicorandil [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012859 D-ribosylnicotinate Nicotinic acid Unclear D-ribosylnicotinate [2]
MR004350 Nicotinyl alcohol Nicotinic acid Unclear Nicotinyl alcohol [3]
MR012775 Trientine NA Conjugation - Acetylation Trientine [4], [5]
MR003986 Nicotinamide (NAM) Nicotinic acid Unclear SRT-647 [6]
MR005792 Nicotinamide (NAM) NA Unclear Deamido-NAD [7]
MR012865 Nicotinamide (NAM) Nicotinic acid Unclear D-ribosylnicotinate [2]
⏷ Show the Full List of MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012860 Nicotinic acid NaMN Unclear D-ribosylnicotinate [2]
MR005793 NA NaMN Unclear Deamido-NAD [7]
References
1 Pharmacokinetics of nicorandil
2 Nicotinamide riboside and nicotinic acid riboside salvage in fungi and mammals. Quantitative basis for Urh1 and purine nucleoside phosphorylase function in NAD+ metabolism
3 Antihyperlipidemic properties of beta-pyridylcarbinol. A review of preclinical studies
4 Triethylenetetramine pharmacology and its clinical applications
5 Comparison of the Pharmacokinetic Profiles of Trientine Tetrahydrochloride and Trientine Dihydrochloride in Healthy Subjects
6 BST1 regulates nicotinamide riboside metabolism via its glycohydrolase and base-exchange activities
7 Molecular identification of human glutamine- and ammonia-dependent NAD synthetases. Carbon-nitrogen hydrolase domain confers glutamine dependency. J Biol Chem. 2003 Mar 28;278(13):10914-21.

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