Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR012860)
Formula
SVG example
Reactant Nicotinic acid Product NaMN
Reactant Info Product Info
Metabolic Enzyme Nicotinate phosphoribosyltransferase (NPT1) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012859 D-ribosylnicotinate Nicotinic acid Unclear D-ribosylnicotinate [1]
MR010728 Nicorandil Nicotinic acid Unclear - Unclear Nicorandil [2]
MR004350 Nicotinyl alcohol Nicotinic acid Unclear Nicotinyl alcohol [3]
MR012775 Trientine NA Conjugation - Acetylation Trientine [4], [5]
MR003986 Nicotinamide (NAM) Nicotinic acid Unclear SRT-647 [6]
MR005792 Nicotinamide (NAM) NA Unclear Deamido-NAD [7]
MR012865 Nicotinamide (NAM) Nicotinic acid Unclear D-ribosylnicotinate [1]
⏷ Show the Full List of MR
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012866 D-ribosylnicotinate NaMN Unclear D-ribosylnicotinate [1]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012861 NaMN NaAD+ Unclear D-ribosylnicotinate [1]
MR005794 NaMN NaAD(Deamido-NAD) Unclear Deamido-NAD [7]
References
1 Nicotinamide riboside and nicotinic acid riboside salvage in fungi and mammals. Quantitative basis for Urh1 and purine nucleoside phosphorylase function in NAD+ metabolism
2 Pharmacokinetics of nicorandil
3 Antihyperlipidemic properties of beta-pyridylcarbinol. A review of preclinical studies
4 Triethylenetetramine pharmacology and its clinical applications
5 Comparison of the Pharmacokinetic Profiles of Trientine Tetrahydrochloride and Trientine Dihydrochloride in Healthy Subjects
6 BST1 regulates nicotinamide riboside metabolism via its glycohydrolase and base-exchange activities
7 Molecular identification of human glutamine- and ammonia-dependent NAD synthetases. Carbon-nitrogen hydrolase domain confers glutamine dependency. J Biol Chem. 2003 Mar 28;278(13):10914-21.

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