General Information of This Metabolic Reaction (MR) (ID: MR011011)
Formula
SVG example
Unclear
Reactant Adenosine triphosphate Product Adenosine diphosphate
Reactant Info Product Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR008287 DIADENOSINE TETRAPHOSPHATE ADP Hydrolysis - Hydrolysis DIADENOSINE TETRAPHOSPHATE [1]
MR000070 AMP ADP Other reaction - Phosphorylation Adenosine [2], [3]
MR000075 ATP ADP Other reaction - Dephosphorylation Adenosine [2], [3]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR011012 Adenosine diphosphate Adenosine Phosphate Unclear - Unclear Adenosine triphosphate [4]
MR000073 ADP ATP Other reaction - Phosphorylation Adenosine [2], [3]
MR000072 ADP AMP Other reaction - Dephosphorylation Adenosine [2], [3]
References
1 Three diadenosine 5',5''-P1,P4-tetraphosphate hydrolytic enzymes from Physarum polycephalum with differential effects by calcium: a specific dinucleoside polyphosphate pyrophosphohydrolase, a nucleotide pyrophosphatase, and a phosphodiesterase
2 Adenosine Metabolism: Emerging Concepts for Cancer Therapy Cancer Cell. 2019 Dec 9;36(6):582-596. doi: 10.1016/j.ccell.2019.10.007.
3 Purine signaling pathway dysfunction in autism spectrum disorders: Evidence from multiple omics data. Front Mol Neurosci. 2023 Feb 3;16:1089871. doi: 10.3389/fnmol.2023.1089871.
4 ATP and its metabolite adenosine cooperatively upregulate the antigen-presenting molecules on dendritic cells leading to IFN- production by T cells

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